We designed a multicenter, double-blind, placebo-controlled trial to explore if vitamin K2 can effectively manage nocturnal leg cramps (NLCs).
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Read More
Most Useful Reviews
10
Leg pain relief
7 people found this helpful
Very helpful! For about a year, I suffered from heaviness in my legs, making it painful to walk for long periods. After taking vitamin K2 from this company, everything disappeared. I can now move freely like a swallow! I purchased more, as this product has become my number one!
Read More
9
Effective combination
2 people found this helpful
Be sure to take with D3! I combined it with D3, and if I use only D3 without K2, I experience leg cramps and discomfort. This combination works wonders!
Read More
10
Relief for father
For many years, my dad has relied on this drug for leg pain, and it has truly helped. Whenever he stops taking it, the pain in his legs returns immediately. He prefers this particular brand, as others have proven less effective.
We designed a multicenter, double-blind, placebo-controlled trial to explore if vitamin K2 can effectively manage nocturnal leg cramps (NLCs).
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
Read More
User Reviews
USERS' SCORE
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Based on 10 Reviews
8.8
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Negative Reviews
10
Leg pain relief
7 people found this helpful
Very helpful! For about a year, I suffered from heaviness in my legs, making it painful to walk for long periods. After taking vitamin K2 from this company, everything disappeared. I can now move freely like a swallow! I purchased more, as this product has become my number one!
Read More
9
Effective combination
2 people found this helpful
Be sure to take with D3! I combined it with D3, and if I use only D3 without K2, I experience leg cramps and discomfort. This combination works wonders!
Read More
10
Relief for father
For many years, my dad has relied on this drug for leg pain, and it has truly helped. Whenever he stops taking it, the pain in his legs returns immediately. He prefers this particular brand, as others have proven less effective.
Read More
9
Muscle pain relief
The drug is for those with poor protein absorption and should be taken after appropriate tests. My doctor prescribed it, as it doesn't involve D3 and protein. After taking this drug, my muscle tone improved significantly, and pain in my legs disappeared.
Read More
9
Nights without cramps
Excellent vitamins! I was prescribed this for taking with calcium and magnesium. My legs were "drooping" at night, but after starting the vitamin complex, I noticed I could sleep peacefully without experiencing leg cramps or tightening.
Leg cramps, often referred to as "charley horses," are sudden, involuntary contractions of one or more muscles in the leg. They typically occur in the calf muscles but can also affect the thighs and feet. These cramps can be quite painful and may last from a few seconds to several minutes. While the exact cause of leg cramps is not always clear, they can be triggered by factors such as dehydration, prolonged sitting or standing, electrolyte imbalances, or physical activity, especially in those who are not used to vigorous exercise.
Treatment for leg cramps often involves stretching the affected muscle gently, applying heat or cold to the area, and ensuring adequate hydration. For some, dietary adjustments to include more potassium, magnesium, and calcium may help prevent future occurrences. If cramps are frequent or severely debilitating, it may be beneficial to consult a healthcare provider for a more tailored approach. Understanding the underlying causes of leg cramps can lead to more effective management strategies, improving overall comfort and mobility.
Vitamin K is a fat-soluble vitamin crucial for various bodily functions, particularly in the clotting process of blood. It exists in two primary forms: K1 (phylloquinone), which is primarily found in leafy green vegetables like spinach and kale, and K2 (menaquinone), which is found in fermented foods and certain animal products. Vitamin K plays a significant role in the synthesis of proteins that regulate blood coagulation and is also essential for bone metabolism, assisting in the binding of calcium to bones and other tissues.
Deficiencies in vitamin K can lead to increased bleeding and bruising, and in severe cases, it may contribute to bone weakness. While most people can obtain adequate amounts of vitamin K through a balanced diet rich in vegetables and fermented foods, those with certain medical conditions or who are on specific medications may require monitoring and supplementation. Incorporating a variety of nutrient-dense foods into your diet is the best way to ensure you get enough vitamin K for optimal health.
Based on user reviews, the time it typically takes to see results from taking this supplement for leg cramps can vary. Some users report immediate relief, indicating improvements as soon as two days after starting their regimen, particularly when combined with Vitamin D3 Read Review. Others, however, may find that it takes longer to experience significant relief; for example, one user mentioned a year of discomfort before finding effective results with Vitamin K2 Read Review.
Overall, users advocate for consistency in taking the supplement, with many noting an almost immediate impact on discomfort when used in conjunction with other vitamins, such as D3 Read Review. Recommendations highlight the importance of individual health variables and suggest that while some may feel an effect within a short period, others may need to continue for longer to see the best results.
Recent scientific research indicates that vitamin K2 may be effective in alleviating nocturnal leg cramps (NLCs). A multicenter, double-blind, placebo-controlled trial conducted in China involved older adults who regularly experienced leg cramps. Participants were randomly assigned to receive either vitamin K2 or a placebo over an 8-week period. The results were promising, as those receiving vitamin K2 showed a significant reduction in the frequency, duration, and intensity of their cramps compared to the placebo group [1].
The findings not only highlight the potential of vitamin K2 as a viable option for managing nocturnal leg cramps but also emphasize its safety profile throughout the trial. With effective results and an encouraging safety record, vitamin K2 could be a noteworthy consideration for individuals seeking relief from leg cramps.
Based on user reviews, many have reported substantial improvements in their leg-related symptoms after incorporating vitamin K2 into their regimen. One user even shared that after a year of suffering from leg heaviness and pain, they experienced complete relief soon after starting vitamin K2, allowing them to move freely again Read Review. Additionally, users frequently noted that combining vitamin K2 with other supplements, particularly vitamin D3, resulted in enhanced effects, such as reduced leg cramps and improved overall comfort Read Review.
Many users reported a decrease in leg pain and cramps after consistent use of the supplements. For instance, one individual highlighted their father's reliance on this product for leg pain relief, noting its crucial role in managing symptoms effectively Read Review. Furthermore, another user mentioned significant improvements in muscle tone and a reduction in leg pain after taking the vitamin, coupled with a sense of better sleep quality Read Review. Overall, while results can vary from person to person, several users have shared encouraging experiences that suggest vitamin K2 may be beneficial for alleviating leg discomfort.
Based on user reviews, many have reported significant benefits when combining vitamin K2 with other supplements for managing leg cramps. A prevailing theme among users is the strong recommendation to take vitamin K2 alongside Vitamin D3. For instance, one user shared that they experience leg cramps and discomfort when only taking D3, but when integrating K2 into their regimen, they found remarkable relief Read Review. Similarly, another user noted an immediate improvement in their symptoms after starting a combination of Vitamin D3 and K2, eliminating leg cramps within just two days Read Review.
Furthermore, several users indicated that incorporating K2 with other minerals, such as calcium and magnesium, has led to enhanced effects. One reviewer stated that the supplement helped alleviate nighttime leg issues and allowed for peaceful sleep Read Review. Another confirmed a noticeable decrease in leg cramps after combining it with calcium, wishing they had started this combination sooner Read Review. Overall, users suggest that the synergy between vitamin K2 and both Vitamin D3 and minerals can significantly improve leg-related discomfort.
Users report varied experiences with Vitamin K for treating leg cramps, with many indicating positive results when combined with Vitamin D3. For instance, one reviewer experienced a significant reduction in leg cramps after taking Vitamin K2 alongside D3, stating, "if I use only D3 without K2, I experience leg cramps" Read Review. Others have also noted that the combination of these vitamins contributed to better calcium absorption and reduced muscle pains, leading to more restful sleep Read Review.
While specific dosage recommendations were not directly provided by users, there is a consensus suggesting that taking Vitamin K2, particularly in conjunction with D3, can lead to noticeable improvements in leg discomfort. Some users mentioned that they began noticing benefits shortly after commencing their regimen—one said they hadn’t experienced any leg cramps just two days in Read Review. Overall, the general approach appears to advocate for combining K2 with D3 for best results in alleviating leg cramps.
9
No cramps so far
Naturally Occurring Vitamin K2! I learned that taking calcium alone could lead to osteoporosis and potentially cause leg cramps. Immediately, I ordered Vitamin D3 and Vitamin K2. It's only been two days since I started taking them, but so far, I haven't experienced any leg cramps.
10
Leg pain relief
7 people found this helpful
Very helpful! For about a year, I suffered from heaviness in my legs, making it painful to walk for long periods. After taking vitamin K2 from this company, everything disappeared. I can now move freely like a swallow! I purchased more, as this product has become my number one!
9
Effective combination
2 people found this helpful
Be sure to take with D3! I combined it with D3, and if I use only D3 without K2, I experience leg cramps and discomfort. This combination works wonders!
10
Relief for father
For many years, my dad has relied on this drug for leg pain, and it has truly helped. Whenever he stops taking it, the pain in his legs returns immediately. He prefers this particular brand, as others have proven less effective.
9
Muscle pain relief
The drug is for those with poor protein absorption and should be taken after appropriate tests. My doctor prescribed it, as it doesn't involve D3 and protein. After taking this drug, my muscle tone improved significantly, and pain in my legs disappeared.
9
Nights without cramps
Excellent vitamins! I was prescribed this for taking with calcium and magnesium. My legs were "drooping" at night, but after starting the vitamin complex, I noticed I could sleep peacefully without experiencing leg cramps or tightening.
9
Better calcium absorption
I am very pleased! With vitamin K2, calcium absorption has notably improved. I’ve experienced fewer leg cramps and muscle pains, and my sleep has improved. I regret not taking K2 sooner with my calcium. I advise everyone to consider vitamin K2, as it's included in this supplement!
9
Vitamin K2 reduces nocturnal leg cramps
Vitamin K2 in Managing Nocturnal Leg Cramps: A Randomized Clinical Trial.
We designed a multicenter, double-blind, placebo-controlled trial to explore if vitamin K2 can effectively manage nocturnal leg cramps (NLCs).
Conducted in China with older adults experiencing regular cramps, participants were randomly assigned to receive either vitamin K2 or a placebo for 8 weeks. Remarkably, our findings demonstrated that vitamin K2 significantly reduced the frequency, duration, and intensity of NLCs, making it a promising option for those suffering from this discomfort.
Notably, the treatment showed good safety profiles, reinforcing its potential utility in managing leg cramps.
References
Tan J, Zhu R, Li Y, Wang L, Liao S, et al. Vitamin K2 in Managing Nocturnal Leg Cramps: A Randomized Clinical Trial. JAMA Intern Med. 2024;184:1443. doi:10.1001/jamainternmed.2024.5726